The grill will be acting like a window yes, but it doesn't need acryl. It can both act like an intake/outtake hole and window.
Intergrating the veins into the watercooling would be difficult. Those small tubes would dramaticaly increase the flow resistance.
But i can make it look like it's in a watercooling circuit. Just a pump, reservoir and some sci-fi looking parts around it. (like its a machine for adding oxigen to blood.) When the water or blood, just how you wanted to call it, is flowing it will be prevented of sinking to the bottom of the reservoir and form a residue.